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Amlodipine
Amlodipine is a calcium channel blocker that dilates systemic arterioles. It is the most effective drug for treating feline hypertension, with the fewest side effects. It is also effective in dogs, though literature documentation is less extensive. A generic version has recently become available, improving affordability.
Key Facts
- Calcium channel blocker -- dilates blood vessels to lower pressure
- Most effective antihypertensive for cats
- Can be given orally or applied transdermally (though oral is more effective)
- Generic version now available (previously expensive, especially for dogs)
- In a study of 141 cats, blood pressure was stabilized within 1-2 rechecks (median 20 days) in 96% of cats
- 50% of cats eventually needed a dose increase
- Species: dogs and cats (most literature on cats)