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Insulin Therapy

Insulin therapy is the primary treatment for diabetes-mellitus in dogs and cats. It involves regular subcutaneous injections to replace the insulin the pancreas can no longer produce adequately.

Key Facts

  • Dogs: virtually all are insulin-dependent (Type I-like); diabetes is usually permanent
  • Cats: many have Type II-like diabetes; remission possible if blood sugar normalized quickly
  • Common insulins for cats: Vetsulin (pork), ProZinc/PZI, Lantus/Glargine, Humulin N
  • Administered by syringe or injection pen; usually twice daily ~12 hours apart
  • U-40 syringes for 40 unit/cc insulins; U-100 syringes for 100 unit/cc insulins -- must match
  • Feed before giving insulin to avoid hypoglycemia
  • Vary injection site to prevent scarring and fat deposits
  • Oral alternatives for some cats: bexagliflozin, velagliflozin, glipizide
  • Insulin stored at room temperature lasts shorter; refrigeration extends to 4-6 months
  • Never alter dose without veterinary guidance
  • Species: dogs and cats

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