Condition3 connections · 1 source
Ibuprofen Toxicity
Ibuprofen and other NSAIDs (non-steroidal anti-inflammatory drugs) are extremely toxic to dogs and cats. Cats are especially sensitive due to their limited ability to metabolize these drugs.
Key Facts
- Common cause of pet poisoning; owners may give human pain medication to pets
- Causes GI ulceration, kidney failure, and liver damage
- Cats are 2-5x more sensitive than dogs due to deficient glucuronidation
- Signs: vomiting (often bloody), diarrhea, abdominal pain, lethargy, kidney failure
- Treatment: decontamination (if recent), GI protectants, IV fluids, monitoring
- Never give human pain medications to pets without veterinary guidance
- Other dangerous NSAIDs: naproxen, aspirin (especially in cats), acetaminophen (fatal in cats)
- Species: dogs and cats